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What is FRα? What is FRα? How does ELAHERE work?

What is FRα and why is it important?

Folate receptor alpha, or , is a protein often found in people with ovarian cancer. Your doctor may refer to it as a biomarker.

Testing for FRα can help your doctor determine if ELAHERE is right for you.

  • Before you start treatment, your doctor will test a sample from your tumor to confirm that your cancer is FRα+. Your doctor may be able to use tissue stored from an earlier biopsy or surgery for testing
  • If you have already received a biopsy or had surgery for ovarian cancer, ask your doctor if your cancer has been tested for FRα

ELAHERE is the first treatment for people with platinum-resistant ovarian cancer that targets FRα in order to deliver medicine directly into cells.

Graphic of a coral magnifying glassDefine: Ovarian cancer: Ovarian cancer is used throughout this site to refer to ovarian cancer, fallopian tube cancer, and primary peritoneal cancer.Biomarkers: Genes, proteins, or other substances that can be tested, found, and measured to give your doctor more information about your cancer—like whether the tumor is growing or how well you may respond to certain treatments.FRα+: A biomarker test result that means you have a certain amount of FRα on the surface of your cancer cells. If your ovarian cancer is FRα positive, ask your doctor if ELAHERE is right for you.

Graphic of the female reproductive system with FR⍺ in a pink bubble

How is ELAHERE designed to target and kill cancer cells?

ELAHERE may affect cancer cells as well as certain healthy cells in the body, which can cause side effects.

ELAHERE is a type of treatment called an . ADCs are different from traditional chemotherapies. They are designed to attack cancer in a targeted way.

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ELAHERE attaches to the outside of the cell

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After binding to FRα, ELAHERE is taken into the cell

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ELAHERE releases a strong cancer-killing drug inside the cell

Graphic of cancer-killing drug impacting other cells

The cancer-killing drug can also impact other nearby cells that may or may not be cancerous

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Is ELAHERE right for me?

See if ELAHERE may be an option for you.

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Discover how ELAHERE can help

See how ELAHERE worked in a clinical study of women with ovarian cancer.

See the Results
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