How was ELAHERE studied?
ELAHERE may help stop cancer from progressing
In a clinical study of 453 people with FRα-positive, platinum-resistant ovarian cancer, ELAHERE helped extend the time to disease progression compared with traditional chemotherapy
Median time to disease progression
More time without the cancer growing or spreading with ELAHERE
This is called median progression-free survival. Median progression-free survival is the length of time that the treatment stops the cancer from growing or getting worse for half of the people. A median is the middle number in a group of numbers that are listed from lowest to highest.
Traditional chemotherapy in the clinical study included anti-cancer drugs that are not targeted and do not contain a material called platinum
Some people taking ELAHERE lived longer
ELAHERE was proven to help people live longer compared with traditional chemotherapy in a clinical study of 453 people with FRα-positive, platinum-resistant ovarian cancer.
Median overall survival
This is called median overall survival. Median overall survival is the length of time that half of the people were alive after starting treatment. A median is the middle number in a group of numbers that are listed from lowest to highest
A chance for better response is here
In the same clinical study, more people’s tumors shrank by at least 30% or disappeared when treated with ELAHERE vs when treated with traditional chemotherapy
Overall response*
VS
The decrease in tumor size lasted a median of 6.8 months in those treated with ELAHERE and 4.5 months in those treated with traditional chemotherapy.
Overall response is a measure of all people who had either a complete or partial response
*In the clinical study, 225 people treated with ELAHERE and 224 people treated with traditional chemotherapy were eligible to be evaluated for overall response
Potential side effects with ELAHERE
ELAHERE can cause serious side effects, including:
- Eye problems. Eye problems are common with ELAHERE and can also be severe. Tell your healthcare provider right away if you develop any eye problems during treatment with ELAHERE, including blurred vision, dry eyes, sensitivity to light, eye pain, eye redness, or new or worsening vision changes
- Lung problems (pneumonitis). ELAHERE can cause severe or life-threatening inflammation of the lungs that may lead to death. Tell your healthcare provider right away if you get new or worsening symptoms, including trouble breathing, shortness of breath, cough, or chest pain
- Peripheral neuropathy. Nerve problems called peripheral neuropathy are common with ELAHERE and can also be severe. Your healthcare provider will monitor you for signs and symptoms of nerve problems. Tell your healthcare provider if you get new or worsening numbness, tingling, burning sensation, or pain in your hands or feet or muscle weakness
The most common side effects and abnormal lab results include:
- Increased liver enzymes in the blood
- Feeling tired
- Blurred vision
- Nausea
- Diarrhea
- Stomach-area (abdominal) pain
- Changes in the cornea (part of the eye)
- Peripheral neuropathy
- Muscle, bone, or joint pain
- Decreased red or white blood cell counts
- Decreased platelets
- Decreased magnesium level in the blood
- Dry eye
- Constipation
- Vomiting
- Decreased albumin level in the blood
- Decreased appetite
Your healthcare provider may change your dose of ELAHERE, delay treatment, or completely stop treatment if you have certain side effects
Due to side effects: 9% of people stopped treatment, 54% of people had dose delays, 34% of people had their dose reduced, and 24% of people reported serious adverse events
Of those treated with ELAHERE in a clinical study, 1% experienced hair thinning or hair loss.
These are not all the possible side effects of ELAHERE. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1‑800‑FDA‑1088
Call 1–833–ELAHERE for ELAHERE Support Services
Receive future updates about ELAHERE
FRα=folate receptor alpha.
You are about to leave this site
You are about to leave ELAHERE.com and enter a website operated by a third party. ImmunoGen does not control, is not responsible for, and makes no representation as to the accuracy or any other aspect of such resource or the privacy practices of such third party. Would you like to continue?